![]() The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. Its antiemetic and antivertigo effects are not fully understood, but its central anticholinergic properties are partially responsible. It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Meclizine is an antagonist at H 1 receptors. Therefore, caution should be used when administering meclizine to the elderly. Elderly Īs with any anticholinergic agent, meclizine may cause confusion or aggravate symptoms in those with dementia in the geriatric population (older than 65 years). The consumption of alcohol while under the influence of meclizine may result in additional drowsiness. Users are advised not to operate heavy machinery while under the influence. Drowsiness ĭrowsiness may result as a side effect of taking meclizine. Symptoms of a serious allergic reaction may include rash, itching, swelling, severe dizziness, and trouble breathing. A very serious allergic reaction to this drug is unlikely, but immediate medical attention should be sought if it occurs. Meclizine has been shown to have fewer dry mouth side effects than the traditional treatment for motion sickness, transdermal scopolamine. Some common side effects such as drowsiness, dry mouth, and tiredness may occur. Meclizine may be used to treat vertigo, such as in those with Ménière's disease. Meclizine may not be strong enough for especially sickening motion stimuli and second-line defenses should be tried in those cases. The drug is safe for treating nausea in pregnancy and is a first-line therapy for this use. Meclizine is effective in inhibiting nausea, vomiting, and dizziness caused by motion sickness. Meclizine should be taken with caution in the elderly due to increased risk of confusion and amnesia. Safety and efficacy in children younger than twelve years of age has not been established therefore, use in this population is not recommended. Meclizine is used to treat symptoms of motion sickness. In 2020, it was the 142nd most commonly prescribed medication in the United States, with more than 4 million prescriptions. ![]() It is available as a generic medication and often over the counter. Meclizine was patented in 1951 and came into medical use in 1953. It is believed to work in part by anticholinergic and antihistamine mechanisms. ![]() Use in pregnancy appears safe, but has not been well studied while use in breastfeeding is of unclear safety. Serious side effects may include allergic reactions. ![]() Ĭommon side effects include sleepiness and dry mouth. Effects generally begin in an hour and last for up to a day. Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness ( vertigo). ![]()
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